Holistic Bliss Keto There has been a heated debate over which is the more effective appetite suppressor between Hoodia and Glucose since the discovery of the active ingredient in Hoodia Gordonii called P57 a decade ago. There is a clear and distinctive winner between the two, but its a matter of understanding how they work before you go ahead and pick the method you would like to follow. I will start off with Glucose and compare the two.